Inhibition of rat platelet aggregation by the diazeniumdiolate nitric oxide donor MAHMA NONOate
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منابع مشابه
Inhibition of morphine tolerance within the rat nucleus accumbens by nitric oxide
The role of glutamate receptors within the nucleus accumbens in morphine tolerance has been postulated. Previous studies have reported that glutamate receptors exert their effects in part through the release of nitric oxide (NO). In the present study, the effect of intra-accumbal injections of L-arginine, the NO precursor and L-NAME, the NOS inhibitor on the morphine tolerance in Wistar rats (2...
متن کاملInhibition of morphine tolerance within the rat nucleus accumbens by nitric oxide
The role of glutamate receptors within the nucleus accumbens in morphine tolerance has been postulated. Previous studies have reported that glutamate receptors exert their effects in part through the release of nitric oxide (NO). In the present study, the effect of intra-accumbal injections of L-arginine, the NO precursor and L-NAME, the NOS inhibitor on the morphine tolerance in Wistar rats (2...
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OBJECTIVE To determine the effect of rat trophoblast cell suspensions on adenosine diphosphate (ADP)-induced platelet aggregation. MATERIALS AND METHODS The trophoblasts were isolated from ectoplacental cones (a preplacental tissue very rich in trophoblasts) developed in rat embryos on day 12 of pregnancy (normal period of gestation: 22-23 days). Platelet-rich plasma (PRP) was obtained from a...
متن کاملThe effect of DETA NONOate, a nitric oxide donor, on the rate of collagen synthesis in rat as an animal model of diabetes
Exogenous nitric oxide donors such as DETA NONOate, spontaneously release nitric oxide. This study aimed to investigate the effect of DETA NONOate as a nitric oxide releasing drug on the rate of collagen synthesis during the impaired wound healing in a rat model of diabetes. Twelve male Sprague–Dawley rats were transferred into separate metabolic cages. Nine days before wounding, the rats were ...
متن کاملPharmacological profile of a nitric oxide donor spermine NONOate in the mouse corpus cavernosum.
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ژورنال
عنوان ژورنال: British Journal of Pharmacology
سال: 2002
ISSN: 0007-1188
DOI: 10.1038/sj.bjp.0704971